Genes
Oligo Pools
NGS
Variant Libraries
Synthetic Controls
Antibody Discovery
IVDR Solutions
Powering AI-Based Protein Engineering With Scalable Data
"Twist enables us by allowing routine synthesis of tens or hundreds of thousands fully defined sequences."
A-Alpha Bio
Fine tune, iterate, and train with Twist
Fast Turnaround for Fast Iterations
Twist provides rapid, high-fidelity DNA synthesis alongside fast antibody production and characterization, giving you both the sequences and the protein-level data needed to advance your designs. This quick access to validated constructs and assay readouts support more iterations, more learning, and confidence in your results.
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Model Build Phase
With high-quality datasets, researchers can train and refine their AI models. Twist delivers the accuracy and consistency trusted by leading discovery teams, ensuring your training data, validation datasets, and experimental results all reflect the same quality standard.
Model Test Phase
Model success in silico often fails to translate to the laboratory environment. This is why wet lab validation is necessary. Twist enables the validation of your AI outputs whether you are screening thousands of new genes for trait discovery or characterizing antibody candidates.
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CASE STUDY
A CRE.AI.TIVE application of AI: Engineering a more resilient global food supply
“Out of all the solutions we have tried, Twist’s oligos are the most faithful to our designs. We absolutely need this fidelity when we’re validating AI outputs.”
Colleen Drapek, PhD
Lead R&D Scientist, Trait Discovery
AI’s Future Hinges On The Wet Lab
“The result was a much more efficient path to antibody optimization.”
Twist Biosciences
Colby Souders, PhD
Chief Scientific Officer,
Twist Bioscience
Model Learn Phase
After AI/ML models downselects the design space and proposes an initial set of candidates, researchers must generate real-world wet-lab data to understand how those sequences actually perform. In silico screening can prioritize enzyme or antibody sequence variants, but only physical assays provide the ground-truth measurements needed to train, refine, or select AI-generated designs.
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
