Meeting future food demands will require more than conventional approaches. Twist enables scientists to address climate, pathogen, and yield challenges with high-throughput NGS and synthetic biology tools built for research into AgBio and animal health.
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Traditional breeding for trait selection can be a time-intensive process. With next generation sequencing (NGS), the discovery of genes and mutations linked to key traits can be shortened from years to just a few hours. Precision breeding can then be achieved by screening individuals within larger populations for these genes.
Trait discovery and selection are also advancing through in vitro screening. Many researchers are leveraging AI-driven models to predict the impact of sequence variants on organisms. To validate results, CRISPR, reporter assays, and cell-based screens are being used - highly accurate synthesized oligonucleotides are critical for this step.
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What enables some plants and animals to survive extreme temperatures, drought, salinity, or pest pressure? The answers lie in both their genomes and their environments.
NGS can be used to identify genes that improve environmental resilience in crops and livestock. Analysis of soil microbiomes can identify genes that can enhance soil fertility and plant health. Synthetic biology tools can then take those genes and engineer microbes that fix nitrogen more efficiently, sequester more carbon, and grow in adverse conditions.
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Rapid detection and surveillance of plant and animal pathogens is critical to prevent disease spread, maintain a steady food supply and prevent economic loss for producers. NGS can rapidly identify multiple pathogens from the same sample.
Bioengineering can also ensure food security by enhancing crops to have higher nutritional content, a longer shelf-life, or reduced food allergens.
Learn the fundamental techniques powering modern Agricultural Biotechnology
Crop and Livestock Improvement
Accelerating trait discovery and precision breeding
Sustainability and Environmental Resilience
Uncovering resilience traits through genomics and engineered microbes.
Disease Detection and Food Security
Safeguarding food supplies via rapid detection and engineered traits.
Compare individual samples to identify traits that can improve or harm crops and livestock. Screen the entire genome to uncover potential genes of interest. Use custom panels to screen for specific genes within the population.
The data from your library screening is only as good as the accuracy of the genes used to build it. Whether you are screening hundreds, thousands, or tens of thousands of genes in CRIPSR, reporter or other assays, we offer many affordable synthetic DNA choices and formats
Use next-generation metagenomic sequencing to analyze and compare soil microbial populations - helpful in identifying genes that enhance soil fertility and plant health
CRISPR is a popular technique for microbial engineering. Use oligo pools and cloned oligo pools for optimization of gRNA sequences. Synthesize clonal genes built to encode gRNA expression cassettes or knock-in templates.
NGS can help identify genes that confer resistance to drought, salinity, and extreme temperatures, while SynBio can enable the engineering of crops that sequester more carbon or grow in degraded soils.
NGS rapidly identifies plant and animal pathogens, enabling early disease detection, preventing spread. Multiple pathogens and variants can be identified from the same low-input sample.
Synthetic biology tools can be used for CRISPR screens to enhance crops with higher nutritional content, like golden rice enriched with vitamin A, and to reduce allergens in foods.
Twist products are for research use only. Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.
So in four years…we identified a solution, and we put in a new [peanut] variety and we’re getting that out to the growers. So really a magnificent achievement that only is possible because you have this ability to scale genome-wide variation, to scale that WGS, and FlexPrep is really a big part of this.
Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.
The beauty of using these kits is that they are species independent. You don’t need a SNP chip designed by somebody else. You don’t need to make prior assumptions.
Disclaimer: Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.
So in four years…we identified a solution, and we put in a new [peanut] variety and we’re getting that out to the growers. So really a magnificent achievement that only is possible because you have this ability to scale genome-wide variation, to scale that WGS, and FlexPrep is really a big part of this.
Results are specific to the institution where they were obtained and may not reflect the results achievable at other institutions.
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES
Our AgBio experts would love to learn about your sequencing or synthetic biology needs. Complex genomes and custom designs encouraged!
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681 Gateway Blvd
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